- 1140 -- Canon Episcopi becames part of Canon law. It was included in Gratian's authoritative Corpus juris canonici of c. 1140 (Decretum Gratiani, causa 26, quaestio 5, canon 12) and as such became part of canon law during the High Middle Ages.
- 1215 - Fourth Council of the Lateran bans use of Ordeals, Canon 18 (i.e. Trial-by-Ordeal)
- 1252 - Pope Innocent IV allows inquisitors to torture suspected herectics, by issuing public decree, Ad extirpanda. It, however, did not absolve Inquisitors who tortured, i.e. for irregular conduct (re Canon 18)
- 1256 - Pope Alexander IV classifies Sorcery as Heresy, Ut negotium of 1256- reference in pdf. (I cannot find direct English translation/reference). This one did absolve Inquisitors of Canon irregularity.
- 1324 - Trial of Dame Alice Kytelier (Irish) - the events are slightly confusing.
- 1376 - Nicholas Eymerich writes manual for Inquisitors, Directorium Inquisitorum (witch-craft is defined under theology for the first time).
- 1396 to 1406 - Start of witch-hunts in Western Alps (Switzerland and Italy), due principally to Peter von Greyerz. One of the victims is Stedelen.
- 1398 - University of Paris condemns rituals and magic.
- 1475 - Johannes Nider publishes Formicarus, one of history's most important primary source on witch-craft, as viewed by the Church during 15th century.
- 1478 - Start of Spanish Inquisition
- 1484 - Pope Innocent VIIVIII issues Summis desiderantes affectibus, a papal bull regarding witch-craft.
- (and the list goes on ...)