There's proof that Native Americans settled the Americas as far back as 9000/8000 B.C. based on the Folsom site. That's around the time the cradle of western civ was being cunieformed in the Middle East and Egypt.
My personal theory is that the Middle East was a bridge between Europe, Africa, and Asia - allowing the trade of technologies through several different conquests like Alexander, the Roman Empire, the Huns, the Ottoman Empire, Viking raiders, etc. By sharing technological discoveries through trade or subjugation, the regions of Europe, Northern Africa, the Middle East, Asia, and Indo-Asia were able to continue to grow. If a culture was more insular and less inclined to adopt new technologies, or did not find the technologies useful for their current way of life, they suffered for it through lack of growth.
So why did Europe develop so much technology? I want to say because it was smaller than the other continents which made it easier to share technology, diverse because of its location, and had a variety of seasons - which means they had to solve problems for heat, problems for cold, exposure to a variety of diseases and building immunity, problems for travel by land, sea, river - so a whole lot of trading was going down - and much of it facilitated by the roadways set up via the Roman Empire, then the forceful conversion to Christianity to make Latin a common language to share scientific discovery - ironically enough.
But all of this is my speculation. The Americas did have abundance in game and native plants, and many civilizations did develop and flourish to the extent of the Egyptian civilization prior to the Roman Empire. But it's my personal theory that the land was too large and the population was fairly sparse throughout it, leading to several insular civilizations, with only a few developing the roads and trade routes that led to further technological development. It's as if the Irish were never invaded by the Romans, the Vikings, or the Saxons, and thus exposed to written language, architecture, and other technological advances.
But they had 10000 years, and surely tribes had many exchanges between them. So perhaps throughout all the 10000 years, due to the insularity of each civilization, they were faced again and again with huge problems similar to that of the Black Plague in Europe, the changing climate, famine, and other things that can cut a promising technological development short. Perhaps the abundance of game was actually a burden to the development of other technologies - because by using all of the bones and fangs and horns of an animal as weapons, why would you need metal weaponry, which leads eventually to helmets and metal armor, which leads to long-range weaponry... you get the gist.
But truly, I think the problem is that, geographically, there was no Middle East in the American continents. No small area of concentrated trade and science to act as the cradle of Native American civilization, spreading the secrets of farming and metal-working, religion and the number zero.