Charles V (1500 – 1558) famously was ruler over an "empire on which the sun never set". It included large parts of Europe and also colonies in the new world. Charles V was born in the Low Countries and later ruled from Spain, which suggests a mainly North-to-South trajectory for his life in territories that stretched also across continents and from the distant West to the remote East.
What were the westernmost and easternmost locations within the Empire that Charles V visited during his lifetime? (I take it that a visit to the colonies by such a ruler was never contemplated at that time.)