When were both minuscule and majuscule letters used for the first time in the same Latin manuscript?

Question

I understand the first minuscule script appeared in the Latin alphabet in the 3rd century - "New Roman cursive".

My question is: when did a script used both minuscule and majuscule letters in the same text, for the first time?

Answer 1

I'd say Half-Uncial (3rd Century AD) and Carolingian (9th Century AD) scripts; as it says in the Wikipedia text for the latter,

Clear capital letters and spaces between words – norms we take for granted – became standard in Carolingian minuscule [...]

So it was the first time both capitals and minuscules were used in a standard way (instead of ocassionally as with previous minuscule scripts). I don't think it would be possible to pinpoint exactly which was the first text ever to use them together, though.