The joint history of the Eastern Roman Empire and the Sassanid Empire appears to be dominated by almost constant warfare. My understanding is that this weakened both empires to the point of making the rapid Muslim conquest of the entire Sassanid and large parts of the Eastern Roman empire possible.
Was there any significant obstacle to the two empires coming to a lasting peaceful arrangement? If so, was it "material" (e.g. stuff both needed to control) or "cultural" (e.g. the Romans never had to make lasting peace with anyone before, so didn't know how to), or some combination of both?