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I am writing a story for a game and I want to try to make it as accurate as possible. To this end, I would like to find who governed London, England, during the time of the Great Plague, but I can't seem to find it. So, who governed London during the Great Plague?

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The day-to-day running of London remained in the hands of the Lord Mayor. This from the National Archives:

The Lord Mayor and aldermen (town councillors) remained to enforce the King’s orders to try and stop the spread of the disease. The poorest people remained in London with the rats and those people who had the plague. Watchmen locked and kept guard over infected houses. Parish officials provided food.

The poster below is from 1646 but the orders therein are almost identical to the those of 1665.

Orders by the Lord Mayor Source: http://www.bl.uk/learning/images/uk/plague/large3333.html

According to Wikipedia, it was the Privy Council (formal advisors to the king) which took the decision to start household quarantines. Once the plague was out of control (July), King Charles II moved to Oxford, which was where Parliament was held. Others who could also left London, including lawyers, merchants and doctors (!).

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