The ➕-shaped inscription in the first image is not related to the ➕-shaped holes in the other images. Also, neither of these ➕-shapes are specific to Gū chalices, being also found in other types of bronze vessels.
- The ➕-shaped inscription in the first image is the ancestor of the Chinese character 「亞」, and can be thought of as a Shāng Dynasty, non-royal version of the cartouche. This decorative usage was found almost exclusively in Shāng bronze inscriptions, specifying the insignia of a clan, the name of an bureaucratic office position, or certain tribal states mentioned in Shāng records (方國).
- The ➕-shaped holes in the other images are casting remnants caused by spacers or chaplets - devices which control the thickness of a mold wall or to support the mold core during the mold-casting process. See the HarvardX video How ancient Chinese bronzes were created for an overview of the piece mold technique for casting bronzes - chaplets are mentioned at around 1m57s.
Although these ➕-shapes are not related to each other, they are both features mainly found in Shāng bronzes, and quickly disappeared among bronze artifacts after the dynasty's fall.
Glyph evolution and usages of 「亞」
Aerial view of the Royal Tomb Historic Site of the Ruins of Yīn (殷墟王陵遺址, 36°08'22.4"N 114°18'07.5"E), site of the last Shāng capital, showing multiple 亞-shaped burial chambers found on the site, with tomb passages as prominent offshoots off large main chambers.
Glyph evolution of 「亞」
「亞」 depicts ancient passageways and entrances to royal tombs, which were the iconic architecture of Shāng ceremonial halls. The modern meaning of 「亞」, inferior/below/next (in rank), is either a rebus borrowing or an extension of the semantic field (tomb > underground > below > inferior).
From its usage in texts, 「亞」 symbolises some kind of rank or elevated status, and is the name for an ancient office position if it appears as an individual character. For example,
Inscription record #5708 (upper side) from 《甲骨文合集》. (Left) Passage of interest boxed in red. (Right) Transcription of the passage into regular script, reproduced in text below. Parentheses indicate the interpretation of the character using modern cognates. Non-encoded characters are decomposed using ideographic description sequences. ⍁ is a placeholder for non-transcribed characters.
Divination on the day of yǐhài, it is asked: "Shall the cavalry officers 𢓚, 冓, and ⿰克永 be dispatched to patrol the 䧅 town outskirts, arriving at ⿳亼爿口侯, following ⍁1川 and ⍁2侯?"
Untranslated characters should be tentatively treated as proper nouns of location/geographical names and/or people
邐 guǐ vessel, inscription record #3975 from 《殷周金文集成》. (Left) Image of original passage. (Right) Transcription of the passage into regular script, reproduced in the text below. The last character, 「⿱聑髭」, is a clan name or symbol.
辛子（巳）王酓（飲）多亞𦔻（聽）⿱亯京⿱麗止（就邐 > 即位）易（賜）貝⿱二朋（二朋）⿰用𠆦（用作）⿰大子（大子）丁⿱聑髭 
On the day of xīnsì, the King held a wine ceremony for the court officials. 聽 joined the ceremony and took his seating, and the King bestowed him two 朋 of 貝, which was used to cast this 大子丁 guǐ vessel. ⿱聑髭.
The stand-alone usage of 「亞」, indicating the meaning name of an ancient office position, is also found when 「亞」 appears as a decorative border. If a clan symbol inside 「亞」 is or contains a character that depicts a profession, the clan insignia indicates that the clan may play a specific role in society. The evidence linking decorative 「亞」 borders to professions is circumstantial, however, and these insignia should be primarily interpreted as clan names or clan icons.
亞犬父丁 fāng dǐng vessel, inscription record #1845 from 《殷周金文集成》 The caster was from the ⿴亞犬 clan, and this vessel is for commemorating the caster's father (父) on the fourth day (丁) of ten days. Shāng and Zhōu timekeeping involved 10-day "weeks" named in sequence as 甲乙丙丁戊己庚辛壬癸, together called the heavenly stems. 「犬」 literally means dog.
亞戈 dǐng vessel, inscription record #1447 from 《殷周金文集成》 The caster was from the ⿴亞戈 clan. 「戈」 literally means dagger-axe.
亞魚 dǐng vessel. 「𤉯」, modern form 「魚」, literally means fish. (Left) Image of original passage. (Right) Transcription of the passage into regular script, reproduced in the text below.
On the day of rénshēn, the king bestowed riches to ⿴亞魚 for the casting of a zūn vessel for the commemoration of Elder Brother on the tenth day. 'Tis the sixth month of the seventh year of the King's ascension to the throne, during the memorial of 翼.
亞⿱𤕰𪦾父辛 zūn vessel, inscription record #5746 from 《殷周金文集成》 The clan name/symbol is ⿱𤕰𪦾, and this vessel is for commemorating the caster's father (父) on the eighth day (辛) of ten days.
The creature inside of 「亞」 in your first image,
does not appear to have a consensus in its interpretation, being sometimes identified as a non-specific animal/beast 「獸」 and sometimes interpreted as horse 「馬」. If the creature is a horse, then 「亞」 surrounding horse is a clan insignia which possibly specifies that the clan has something to do with cavalry corps.
Minor note on ➕-shaped holes
Taken from the English-version abstract from the article 《圈足上的鏤孔：試論商代青銅器的泥芯撐技術》 (Perforations above the round base: A discussion of techniques involving clay cores in Shāng-era bronze vessels) by Liú Yù below:
Some square or criss-cross holes commonly seen in the ring-foot of Shang bronze vessels are thought to be caused by clay spacers made in the clay core prior to casting. Clay spacers are some ridges in the clay core, sometimes in the outer-mold, which can maintain the wall thickness, keep mold sections register and help the core fixed. The evolution of clay-spacer technique is related to the development of section-mold casting technology of bronze vessels.
- 小學堂字形演變 (Glyph evolution reference from the Republic of China (Taiwan) Ministry of Science and Technology, RoCMOST)
- Multi-function Chinese Character Database, Research Centre for Humanities Computing, Chinese University of Hong Kong
- 《甲骨文合集》 (Compilation of Oracle Bone Inscriptions) by Guō Mòruò
- 《甲骨文詞組研究》 (Phraseology of Oracle Bone Passages) by RoCMOST
- 《商代金文構形研究》 (Structural Analysis of Bronze Inscription Characters in the Shāng Era) by Fang Yüeh-shan (Master's Thesis)
- Interpretation based on Hú Hòuxuān's 《甲骨續存》 (Continuation of Oracle Bone Archives) 上66 modified with transcription corrections
- 《殷周金文集成》 (Collection of Bronze Inscriptions from the Yīn and Zhōu Dynasties), Institute of Archaeology, Chinese Academy of Social Sciences
- From Hé Línyì's 《聽簋小箋》. Compare Zhengzhang OC reconstructions in the rebus borrowing direction: 「邐」 (/*relʔ/) > 「立」 (/*rɯb/) > 「位」 (/*ɢʷrɯbs/).
- Whole transcription based on , with corrections from [1,8]
- 「朋」 was an ancient unit for money, depicting strands of jade discs, cowrie shells, or coins tied together
- Inscription record given by #NA1040 in 《新收殷周青銅器銘文暨器影彙編》 (Corpus of New Collections of Images and Writing of Bronze Vessels from the Yīn and Zhōu Dynasties)
- Interpretation of 「羽」 given by reading of 四祀𠨘其卣 (《殷周金文集成》5413) in Liú Xiáng et al. 《商周古文字讀本》 (A Reader of Ancient Characters in the Shāng and Zhōu Dynasties)