The Middle East is a transcontinental region in Afro-Eurasia which generally includes Western Asia (except for Transcaucasia), all of Egypt (mostly in North Africa), and Turkey (partly in Southeast Europe). The term has come into wider usage as a replacement of the term Near East (as opposed to the Far East) beginning in the early 20th century. [...] The term "Middle East" has led to some confusion over its changing definitions.
Why and when did this definition change? If "East" means Asia, then clearly Turkey, Syria, Israel, Iraq, etc. (which are often referred to as "Middle East") are not in the middle of Asia. The middle would be countries like India, Kazakhstan and Nepal. (And then the "Far East" would be Korea, Japan, etc; which it is in general usage.) In the past, as above, this region was called the "Near East," which seems to make more sense. Additionally, the Wikipedia definition including part of Southeast Europe would further work against calling it "middle."
One could of course use an absolute description and call this region (excluding North Africa) "Southwest Asia" (Northwest Asia being in Russia, which is another can of worms as to the "Europe or Asia" question), but that term does not seem to be in wide use outside of the US military.