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Were any of the early settlements in America attacked from the sea?

I have a textbook which describes various considerations colonists made in selecting sights for settlements. For example, it says that Jamestown was too swampy, so there were many mosquitoes and ...
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Early instances of bacteriological warfare

Via The Straight Dope, I came across this page which claims that Lord Jeffrey Amherst, commander-in-chief of the Brits in America seriously considered distributing blankets infected with small-pox to ...