I'm not sure why OP rejects Mary Queen of Scots
James Hepburn, 4th Earl of Bothwell, was generally believed to have orchestrated Darnley's death, but he was acquitted of the charge in April 1567, and the following month he married Mary. Following an uprising against the couple, Mary was imprisoned in Loch Leven Castle. On 24 July 1567, she was forced to abdicate in favor of James VI, her one-year-old son by Darnley. Wikipedia
(most of the stuff I've read indicates that her marriage to Bothwell was not voluntary; she was kidnapped and raped).
Boadica may qualify
Boudica's husband, Prasutagus, ruled as a nominally independent ally of Rome and left his kingdom jointly to his daughters and the Roman emperor in his will. However, when he died, his will was ignored, and the kingdom was annexed. According to Tacitus, Boudica was flogged and her daughters raped.