Yes, there has been.
As this infographic shows, there has been a back-migration of the DNA haplogroups C1a and A2a from North America back into Asia.
The infographic is sourced as Tamm E, Kivisild T, Reidla M, Metspalu M, Smith DG, et al. (2007) Beringian Standstill and Spread of Native American Founders. PLoS ONE 2(9): e829. doi:10.1371/journal.pone.0000829.
Other (later) back-migrations might exist; I understood that your question would be answered with one "yes" already and stopped searching at this point.